The Free Bioavailable Testosterone Calculator is designed to assist clinicians.
A aplicação livre de testosterona e calculadora de testosterona biodisponível foi projetada para ajudar os médicos a determinar com precisão os níveis circulantes de testosterona bioativa. Simply plug in the appropriate lab values and push a button for fast, accurate results.
- How to use the Free & Bioavailable Testosterone Calculator
The Free & Bioavailable Testosterone Calculator reduces the risk of errors that can occur when performing complicated calculations by hand. To use the app, input current lab values into the specified boxes for:
Albumina
SHBG
Testosterona
Once lab values are in place, press the calculate button and let the Free & Bioavailable Calculator app do the math.
Free & Bioavailable Testosterone
A testosterona e a di-hidrotestosterona (DHT) circulam no plasma não ligado (livre aproximadamente 2-3 %), ligado a proteínas plasmáticas específicas (SHBG) e fracamente ligadas a proteínas não específicas, como a albumina. The SHBG-bound fraction is biologically inactive because of the high binding affinity of SHBG for testosterone.
Bioavailable testosterone measurement includes the free plus the weakly bound.
Free testosterone measures the free fraction.
Certain health conditions and medications, such as corticosteroids, can affect SHBG levels, impacting total serum testosterone concentration. A combinação de albumina, a globulina de ligação ao hormônio sexual (SHBG) e os níveis de testosterona fornece uma medição mais precisa da concentração total de testosterona sérica.
Free Testosterone Reference Range
Males (16 years and above): 9-30 ng/dL
Females: 0.3–1.9 ng/dL
Bioavailable Testosterone Reference Range
Males:
20-29 years: 83-257 ng/dL
30-39 years: 72-235 ng/dL
40-49 years: 61-213 ng/dL
50-59 years: 50-190 ng/dL
60-69 years: 40-168 ng/dL
>69 years: not established
Females (non-oophorectomized)
20-50 years (on oral estrogen): 0.8-4.0 ng/dL
20-50 years (not on oral estrogen): 0.8-10 ng/dL
>50 years: not established
Disclaimer: Results from this calculator should NOT be solely relied upon in making (or refraining from making)
any decision in any case/ circumstances without the prior consultation of experts or professional persons. Não
responsability whatsoever is assumed for its correctness or suitability for any given purpose.
AVISO! The calculated free and bioavailable testosterone are reliable in most clinical situations, but should
not be relied upon in situations with potential massive interference by steroids binding to SHBG; eg in women
during pregnancy, in men during treatment inducing high levels of DHT (eg transdermal DHT, oral
testosterone) or mesterolon
This calculator was developed at the Hormonology department, University Hospital of Ghent, Belgium. If you have
suggestions to improve this calculator, or for further questions or help contact us Dr. Tom Fiers or Prof. Dr. JM
Kaufman
Lab Source:
http://www.mayomedicallaboratories.com/test-catalog/Clinical+and+Interpretive/83686
Download